日志

兔用抗生素资料

已有 293 次阅读2008-12-7 22:29 |个人分类:药物应用|

对兔兔危险的抗生素

资料来源：http://www.medirabbit.com/Unsafe_medication/dangerous_antibiotics.htm

Name of antibiotic

Effect

Ampicillin	40 to 100% fatal enteritis, dependent on dosage
Amoxicillin	Diarrhea after oral administration.
Cephalexin	Diarrhea after oral administration. Injection of cephalosporin has proven safe.
Clindamycin	50 to 100% fatal enteritis, dependent on dosage
Erythromycin	Diarrhea
Lincomycin	33 to 100% fatal enteritis, dependent on dosage
Minocycline	Reduction of growth rate
Penicillin	Acute and/or chronic enteritis (diarrhea) after oral administration. Injection of cephalosporin has proven safe.
Spectinomycin	Diarrhea
Spiramycin	Nervousness
Tilmicosin	Fatal adverse reaction has been observed. The reaction seems rabbit dependent and it is advised to do a test dose of 5 mg/kg before doubling dosage.
Tylosin	Diarrhea
Vancomycin	Acute toxicity with 100% mortality

安全的抗生素用法
资料来源：http://www.medirabbit.com/Safe_medication/Antibiotics/Safe_antibiotics.htm

Name of antibiotics

Remarks

Dosage

Way

Frequency

Amikacin

Nephrotoxic in dehydrated rabbits.

5-10 mg/kg

8-16 mg/kg

SC, IM, IV

sid, bid, tid

Amoxicillin

(see: Remarks)

*ONLY* as injection, never orally.
Has recently been successfully used in rabbits, to treat infections due to bacteria, whose sensitivity tests indicate that amoxillin is the only effective antibiotic.
No adverse reaction has been noted with injected treatment. *Never* give orally; this has fatal consequences.
Is used sometimes to treat treponematosis.

15 mg/kg (?)

SC, IM

q second day

Azithromycin

Recommended for difficult to treat URI.
May lead to a reduction of appetite.

50mg/kg

sid

Bicillin in Units
(penicillin G procaine and penicillin G benzathine)

(see: Remarks)

*ONLY* as injection.
for treatment of bacterial infections. In rare cases, penicillin treatment leads to:
- a decreased appetite,
- the formation of sterile abscesses.

47.000–84.000 IU/kg

q 2nd/3rd day

Bicillin in mg/kg
(penicillin G procaine and penicillin G benzathine)

(see: Remarks)

*ONLY* as injection.
for treatment of bacterial infections. In rare cases, penicillin treatment leads to:
- a decreased appetite,
- the formation of sterile abscesses.

20 mg/kg – 15 mg/kg

q 2nd/3rd day

Cephalexin

(see: Remarks)

*ONLY* as injection.
Normally no cross reaction with Penicillin, in some cases of renal failure > nephrotoxic

10-15 mg/kg

20 mg/kg

bid, tid

sid

Chloramphenicol

Exceptionally leads to a decrease of appetite

30-50 mg/kg

15 mg/kg

PO, SC, IM

sid

bid

Chlortetracycline

50 mg/kg

bid

Ciprofloxacin

Hindered absorption, when concurrent administration of antacids.

5 – 20 mg/kg

sid, bid

Clopidol

200 mg/kg food

Danofloxacine

1 - 5 mg/kg
(?)

5 mg/kg
(?)

Difloxacine

5 - 10 mg/kg
(?)

2,5 - 5 mg/kg

SC,
IM

Dimetridazole

0.2 mg/ml water

q 12 h.

Doxycycline

2.5 mg/kg

4 mg/kg

bid

sid

Enrofloxacin

(see: Remarks)

High dosage treatment (20 mg/kg) over a longer period of time may lead to seizure.
Cartilage damage in juveniles.
In rare cases, enrofloxacin treatment leads to:
- a decreased appetite,
- the formation of sterile abscesses, if injected. This can be avoided by diluting the solution with a sterile saline solution, 50:50.

5 - 15 mg/kg

PO, SC, IM

bid-sid

Fusidic acid

In eye ointment

1 drop/eye